In a large hospital in Hong Kong, Tong Qian (Zhao Wei), chief surgeon, has just completed a routine inspection. The successive surgeries have made her nerves highly nervous, and some patients are not in good condition after surgery, which has put her spirit under great pressure. At this moment, a man with a gunshot wound was rushed to the hospital. The other party is named Zhang Lixin (Zhong Hanliang), a daring and cunning criminal with a high IQ. Although he was shot in the head, fortunately, he did not suffer a huge trauma. Zhang, who woke up from a coma, refused surgery, as if he was patiently waiting for the opportunity. The police officer Chen Weile (Louis Koo), who monitored and shot him, was highly nervous. He was eager to know the whereabouts of the other party's accomplices and did not hesitate to use illegal means for this. In the hospital where doctors and patients are woven together, in just six hours, the police, doctors and gangsters launched an arduous struggle...