Luke Lee (Wu Zun), a researcher at a biotech company, went deep into an ancient tomb and then lost contact. Jia Lee (Li Bingbing), a doctor of toxicology, learned that his brother Luke was missing, and immediately formed a professional search and rescue team with Mason Burrows (Kelsey Grammer), the president of the pharmaceutical group. Under the leadership of rescue team leader Jack Ridley (Kellan Lutz), the team went to the place where Luke Lee disappeared to search, but accidentally broke into a mysterious underground world, and an unexpected adventure began...