The genius doctor Shen Zhili of the Rejuvenation Valley came out of the valley to find a medicine to resurrect his master, but accidentally bound his life and death to the Twelve Night Master Su Chenche and entered a time loop. Shen Zhili took Su Chenche with him, and together they explored the Moon Palace, went to martial arts conferences, traveled to southern Xinjiang, and experienced a series of life and death adventures. Shen Zhili successfully collected the medicine, but discovered that there was another conspiracy behind it. She and Su Chenche teamed up to break the time loop curse and successfully stopped the villain's plan. It is adapted from the popular work "Shameless" by Weihe Zongzi.